Readily Reconfigurable Continuous-Stirred Tank Photochemical Reactor Platform

نویسندگان

چکیده

A new modular photochemical continuous stirred-tank reactor (CSTR) design is described, based upon the development of light-source units that can be fitted to previously described fReactor CSTR platform. In addition use in homogeneous reactions (e.g., photoredox-catalyzed hydroamination), these are especially well suited handling multiphasic mixtures, exemplified here solid–liquid (Wohl–Ziegler bromination) and gas–liquid (photocatalytic oxidative decarboxylation) reactions. The slurries as input feeds allows for intensification brominations, while nature system facilitates simple integration downstream reaction steps, a synthesis an intermediate antihypertensive drug valsartan.

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ژورنال

عنوان ژورنال: Organic Process Research & Development

سال: 2021

ISSN: ['1083-6160', '1520-586X']

DOI: https://doi.org/10.1021/acs.oprd.1c00428